葛成龙 副研究员
教育经历
2018/09-2021/06：苏州大学，功能纳米与软物质研究院，化学，理学博士
2015/09-2018/06：湘潭大学，化学学院，化学，理学硕士
2011/09-2015/06：湘潭大学，化学学院，高分子材料与工程，工学学士
工作经历
2024/10-至今：苏州大学，功能纳米与软物质研究院，副研究员
2021/07-2024/06：苏州大学，功能纳米与软物质研究院，博士后
所在课题组
殷黎晨教授课题组
主持项目
1. 国家自然科学基金委员会，青年基金项目（主持）
2. 江苏省科技厅，自然科学青年基金项目（主持）
3. 中国博士后科学基金会，第72批面上资助（主持）
研究领域
1. 聚多肽的可控开环聚合及聚合方法学
2. 功能化聚多肽的二级结构调控及生物学效应
3. 高分子递送载体在基因、药物及蛋白跨屏障递送中的研究
代表性研究成果
截止目前，共参与发表sci论文30多篇，其中以第一作者或通讯作者身份在j am chem soc、nano lett、chin j chem、biomacromolecules、j mater chem b等期刊发表论文12篇。
代表性论文
fan zhang#, chenglong ge#, zigang qiao, yu han, lichen yin*, feng ma*. protocol for sirna-mediated u1 snrna knockdown using fluorinated α-helical polypeptide in vitro and in vivo.star protocols, 2024, 5, 103238.
chenglong ge#, jianyin he#, mudan, gan#, yu qian, junliang zhu, fan wu, ziyuan song*, lichen yin*. conformation-switchable polypeptides as molecular gates for controllable drug release. biomacromolecules, 2024, 25, 3373-3383.
chenglong ge, junliang zhu, huan ye, yuansong wei, yuheng lei, renxiang zhou, ziyuan song, lichen yin*. rational construction of protein-mimetic nano-switch system based on secondary structure transition of synthetic polypeptide. j am chem soc, 2023, 145, 11206-11214.
junliang zhu#, yunjie he#, chenglong ge*, wenting si, ziyuan song*, lichen yin*. accelerated ring-opening polymerization of α-amino acid n-carboxyanhydride via inorganic nano-initiators. , 2023, 41, 2476-2482.
chenglong ge#, junliang zhu#, guangqi wu, huan ye, hua lu*, lichen yin*. ros-responsive selenopolypeptide micelles: preparation, characterization, and controlled drug release. biomacromolecules, 2022, 23, 2647-2654.
chenglong ge, yong liu, lichen yin*. effect and regulation of the secondary structure of synthetic poly(α-amino acid) based on ring-opening polymerization. chin sci bull, 2021, 66, 2217-2230.
chenglong ge, huan ye, fan wu, junliang zhu, ziyuan song, yong liu,* lichen yin*. biological applications of water-soluble polypeptides with ordered secondary structures. j mater chem b, 2020, 8, 6530-6547.
chenglong ge#, jiandong yang#, shanzhou duan, yong liu, fenghua meng, lichen yin*. fluorinated α-helical polypeptides synchronize mucus permeation and cell penetration toward highly efficient pulmonary sirna delivery against acute lung injury. nano lett, 2020, 20, 1738-1746.
chenglong ge, ying ling*, shunjie yan, shifang luan, haowen zhang, haoyu tang*. preparation and mechanical properties of strong and tough poly(vinyl alcohol)-polypeptide double-network hydrogels. eur polym j, 2018, 99, 504-510.
chenglong ge, wenjun liu, ying ling*, haoyu tang*. synthesis and thermoresponsive properties of oegylated polypeptide with a lcst at body temperature in water and with a ucst in alcohol or ethanol/water solvent mixture. j polym sci, part a: polym chem, 2018, 56, 163-173.
chenglong ge, liang zhao, ying ling*, haoyu tang*. thermo and ph dual responsive polypeptides derived from “clickable” poly(γ-3-methylthiopropyl-l-glutamate). polym chem, 2017, 8, 1895-1905.
chenglong ge, sheng liu, ce liang, ying ling*, haoyu tang*. synthesis and ucst-type phase behavior of α-helical polypeptides with y-shaped and imidazolium pendants. polym chem, 2016, 7, 5978-5987.
参与编写书籍
chenglong ge, xun liu, lichen yin. gene delivery (chapter 4), in “biomaterial engineering, fluorinated α-helical polypeptides toward pulmonary sirna delivery”. springer nature, edited by youqing shen, huayu tian, xuesi chen. pp 75-96.
责任编辑：杨娟